CAMLG antibody (Middle Region)

Catalog No. ABIN7825297

The Rabbit Polyclonal anti-CAMLG antibody is suitable to detect CAMLG in samples from Human, Mouse and Rat. It has been validated for WB, IHC and FACS.

Quick Overview for CAMLG antibody (Middle Region) (ABIN7825297)

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMLG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CAMLG Antibody

Binding Specificity: Middle Region

Purpose: Anti-CAMLG Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-CAMLG Antibody catalog # A08322-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CAMLG. Human CAMLG shares 91.7% and 95.7% amino acid (aa) sequence identity with mouse and rat CAMLG, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for CAMLG

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Alternative Name: CAMLG

Background: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Molecular Weight: 36 kDa

Gene ID: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway