GNS antibody (AA 224-341)

Catalog No. ABIN7825403

This anti-GNS antibody is a Rabbit Polyclonal antibody detecting GNS in WB and IHC. Suitable for Zebrafish (Danio rerio).

Quick Overview for GNS antibody (AA 224-341) (ABIN7825403)

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GNS Antibody

Binding Specificity: AA 224-341

Purpose: Anti-Zebrafish GNSa Antibody

Characteristics: Anti-Zebrafish-GNSa-Antibody catalog # AZQ4V902. Tested in WB, IHC applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish GNSa recombinant protein (Position: W224-R341).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Zebrafish
Immunohistochemistry, 2-5 μg/mL, Zebrafish

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for GNS

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Alternative Name: GNSa

Background: N-acetylglucosamine-6-sulfatase, also known as glucosamine (N-acetyl)-6-sulfatase, is an enzyme that in humans is encoded by the GNS gene. The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

UniProt: Q4V902

Pathways: Glycosaminoglycan Metabolic Process