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Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 174-203) antibody Primary Antibody

GNS Reactivity: Human IHC (p), WB Host: Rabbit Polyclonal RB19340 unconjugated
Catalog No. ABIN390494
$412.50
Plus shipping costs $45.00
400 μL ABIN390494
400 μL ABIN390494
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Delivery in 10 to 11 Business Days
  • Target
    Glucosamine (N-Acetyl)-6-Sulfatase (GNS)
    Binding Specificity
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 174-203
    Reactivity
    • 35
    • 9
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 31
    • 3
    • 1
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 18
    • 13
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    B, M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This GNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the Central region of human GNS.
    Clone
    RB19340
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Glucosamine (N-Acetyl)-6-Sulfatase (GNS)
    Alternative Name
    GNS (GNS Antibody Abstract)
    Synonyms
    G6S, 2610016K11Rik, AU042285, C87209, N28088, NV14559, N-acetylglucosamine-6-sulfatase, zgc:114066, gns, wu:fi20h10, zgc:55370, glucosamine (N-acetyl)-6-sulfatase, glucosamine (N-acetyl)-6-sulfatase S homeolog, glucosamine (N-acetyl)-6-sulfatase a, N-acetylglucosamine-6-sulfatase, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b, GNS, Gns, gns.S, gns, gnsa, CpipJ_CPIJ000745, Sros_7372, VDBG_04409, Halhy_3165, gnsb
    Background
    GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
    Molecular Weight
    62082
    Gene ID
    2799
    NCBI Accession
    NP_002067
    UniProt
    P15586
    Pathways
    Glycosaminoglycan Metabolic Process
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