CD235b/GYPB antibody (AA 43-91)

Catalog No. ABIN7825418

The Rabbit Polyclonal anti-CD235b/GYPB antibody (ABIN7825418) specifically detects CD235b/GYPB in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CD235b/GYPB antibody (AA 43-91) (ABIN7825418)

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD235b/GYPB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD235b/GYPB Antibody

Binding Specificity: AA 43-91

Purpose: Anti-GYPB Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-GYPB Antibody. Tested in WB, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GYPB recombinant protein (Position: Q43-A91).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD235b/GYPB

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Alternative Name: GYPB

Background:

Background: Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97 % sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.

Gene Full Name: glycophorin B (MNS blood group)

Molecular Weight: 17 kDa

Gene ID: 2994

UniProt: P06028