Hepsin antibody (AA 47-417)
Quick Overview for Hepsin antibody (AA 47-417) (ABIN7825452)
Target
See all Hepsin (HPN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 47-417
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Purpose
- Anti-Hepsin/HPN Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Characteristics
- Anti-Hepsin/HPN Antibody catalog # A02350-1. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Hepsin/HPN recombinant protein (Position: D47-L417). Human Hepsin/HPNshares 90% and 89.2% amino acid (aa) sequence identity with mouse and rat Hepsin/HPN, respectively.
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Hepsin (HPN)
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Alternative Name
- HPN
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Background
- This gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non-catalytic scavenger receptor cysteine-rich chain, which associate via a single disulfide bond. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 51 kDa
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Gene ID
- 3249
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UniProt
- P05981
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Pathways
- Regulation of Hormone Metabolic Process, Sensory Perception of Sound
Target
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