Neurturin antibody (AA 1-197)
Quick Overview for Neurturin antibody (AA 1-197) (ABIN7825604)
Target
See all Neurturin (NRTN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-197
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Purpose
- Anti-NRTN Antibody
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Characteristics
- Anti-NRTN Antibody catalog # A05924-3. Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Neurturin/NRTN recombinant protein (Position: M1-V197). Human Neurturin/NRTN shares 86.3% amino acid (aa) sequence identity with mouse Neurturin/NRTN.
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Isotype
- IgG
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Application Notes
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Neurturin (NRTN)
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Alternative Name
- NRTN
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Background
- Neurturin (NRTN) is a protein that is encoded in humans by the NRTN gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.
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Molecular Weight
- 22 kDa
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Gene ID
- 4902
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UniProt
- Q99748
Target
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