Senataxin (SETX) (AA 29-2544) antibody

Catalog No. ABIN7825794

This Rabbit Polyclonal antibody specifically detects in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for Senataxin (SETX) (AA 29-2544) antibody (ABIN7825794)

Target: Senataxin (SETX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details

Binding Specificity: AA 29-2544

Purpose: Anti-SETX Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SETX Antibody catalog # A02233-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SETX recombinant protein (Position: E29-R2544). Human SETX shares 72.8% amino acid (aa) sequence identity with mouse SETX.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details

Target: Senataxin (SETX)

Alternative Name: SETX

Background: This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Molecular Weight: 303 kDa

Gene ID: 23064

UniProt: Q7Z333