SIPA1 antibody (AA 21-1034)
Quick Overview for SIPA1 antibody (AA 21-1034) (ABIN7825823)
Target
See all SIPA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 21-1034
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Purpose
- Anti-SIPA1 Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Predicted Reactivity
- Human SIPA1 shares 89% amino acid (aa) sequence identity with mouse SIPA1.
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Characteristics
- Anti-SIPA1 Antibody. Tested in WB, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human SIPA1 recombinant protein (Position: D21-L1034). Human SIPA1 shares 89% amino acid (aa) sequence identity with mouse SIPA1.
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
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Alternative Name
- SIPA1
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Background
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Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
Gene Full Name: signal-induced proliferation-associated 1
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Molecular Weight
- 130 kDa
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Gene ID
- 6494
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UniProt
- Q96FS4
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Pathways
- Response to Water Deprivation
Target
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