TTL antibody (AA 104-377)

Catalog No. ABIN7825998

This Rabbit Polyclonal antibody specifically detects TTL in ELISA and WB. It exhibits reactivity toward Mouse and Rat.

Quick Overview for TTL antibody (AA 104-377) (ABIN7825998)

Target: TTL (Tubulin tyrosine Ligase (TTL))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTL antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-TTL Antibody

Binding Specificity: AA 104-377

Purpose: Anti-TTL Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-TTL Antibody catalog # A06710. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TTL recombinant protein (Position: N104-L377). Human TTL shares 95.3% and 95.6% amino acid (aa) sequence identity with mouse and rat TTL, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for TTL

Target: TTL (Tubulin tyrosine Ligase (TTL))

Alternative Name: TTL

Background: TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).

Molecular Weight: 43 kDa

Gene ID: 150465

Pathways: Regulation of Cell Size