VCP antibody (AA 10-512)

Catalog No. ABIN7826030

The Rabbit Polyclonal anti-VCP antibody (ABIN7826030) specifically detects VCP in WB and IHC. The antibody is reactive with Zebrafish (Danio rerio) samples.

Quick Overview for VCP antibody (AA 10-512) (ABIN7826030)

Target: VCP (Valosin Containing Protein (VCP))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VCP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-VCP Antibody

Binding Specificity: AA 10-512

Purpose: Anti-Zebrafish VCP Antibody

Characteristics: Anti-Zebrafish VCP Antibody (ABIN7826030). Tested in WB, IHC applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish VCP recombinant protein (Position: D10-K512).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Zebrafish
Immunohistochemistry, 2-5 μg/mL, Zebrafish

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for VCP

Target: VCP (Valosin Containing Protein (VCP))

Alternative Name: VCP

Background: Predicted to enable ATP hydrolysis activity and polyubiquitin modification-dependent protein binding activity. Acts upstream of or within several processes, including heart contraction, regulation of catabolic process, and striated muscle cell development. Predicted to be located in cytoplasm and site of double-strand break. Predicted to be part of VCP-NPL4-UFD1 AAA ATPase complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain, digestive system, eye, fin bud, and trunk musculature. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2Y, Paget's disease of bone, frontotemporal dementia and/or amyotrophic lateral sclerosis 6, inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1, and inclusion body myositis. Orthologous to human VCP (valosin containing protein).

Molecular Weight: 97 kDa

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway