Recombinant MTAP antibody (AA 95-197)

Catalog No. ABIN7826106

This anti-MTAP antibody is a Rabbit Monoclonal antibody detecting MTAP in IHC. Suitable for Human.

Quick Overview for Recombinant MTAP antibody (AA 95-197) (ABIN7826106)

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MTAP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: 741R

Product Details anti-MTAP Antibody

Binding Specificity: AA 95-197

Purpose: MTAP antibody (741R)

Immunogen: Recombinant human MTAP protein fragment (aa95-197) (exact sequence is proprietary)

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Comment:

Positive Control: Ovary: At least a moderate, nuclear and/or cytoplasmic MTAP staining should be seen in ovarian stroma cells.

Product Description/Background: MTAP antibody validated for immunohistochemistry on 76 different Normal Tissues

Negative Control: Bladder cancer with homozygous 9p deletion: MTAP staining should be absent in cells from urothelial tumors with homozygous 9p deletion.

Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non- hazardous. No MSD required.

Expiry Date: 24 months

Target Details for MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Alternative Name: MTAP

Background: Gene Alias: BDMF, DMSFH, DMSMFH, Epididymis luminal protein 249, HEL249, LGMBF, MeSAdo phosphorylase, Methylthioadenosine phosphorylase, MSAP, MTA phosphorylase, MTAPase, S- methyl-5""-thioadenosine phosphorylase

UniProt: Q13126

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process