Recombinant Mre11 antibody

Catalog No. ABIN7826130

The Rabbit Monoclonal anti-Mre11 antibody (Clone HMV328) (ABIN7826130) specifically detects Mre11 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant Mre11 antibody (ABIN7826130)

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Mre11 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: HMV328

Product Details anti-Mre11 Antibody

Purpose: MRE11 antibody (HMV328)

Immunogen: Recombinant human MRE11 fragment

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Comment:

Positive Control: Colon: A strong nuclear MRE11 staining should be seen in all cells.

Product Description/Background: MRE11 antibody validated for immunohistochemistry on 76 different Normal Tissues

Negative Control: Cancer with previously documented MRE11 negativity: All cancer cells should remain MRE11 negative while a strong nuclear MRE11 staining should be seen in all non-neoplastic cells.

Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37 °C for 60 minutes.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non- hazardous. No MSD required.

Expiry Date: 24 months

Target Details for Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Alternative Name: MRE11

Background: Gene Alias: MRE11 homolog, double strand break repair nuclease , ATLD , HNGS1 , MRE11A , MRE11B

UniProt: P49959

Pathways: DNA Damage Repair