Recombinant ATG9A antibody

Catalog No. ABIN7828028

The Rabbit Monoclonal anti-ATG9A antibody is suitable to detect ATG9A in samples from Human. It has been validated for WB, IHC, IF and FACS.

Quick Overview for Recombinant ATG9A antibody (ABIN7828028)

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ATG9A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A507

Product Details anti-ATG9A Antibody

Purpose: Recombinant ATG9A Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human ATG9A fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for ATG9A

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Alternative Name: ATG9A

Background: MGD,mATG,APG9L,ATG9A,APG9L1,MGD3208,mATG9,APG9 autophagy 9-like 1,APG9 like 1,APG9-like 1,ATG9,ATG9 autophagy related 9 homolog A,ATG9 autophagy related 9 homolog A (S. cerevisiae),Autophagy 9-like 1 protein,Autophagy related 9A,Autophagy related protein 9A,Autophagy-related protein 9A,OTTHUMP00000206046,OTTHUMP00000206048,OTTHUMP00000206049,OTTHUMP00000206062,ATG9A are lipid scramblases that play a role in autophagosome expansion. ATG9A is present in numerous intracellular compartments, including the trans-Golgi network and early and recycling endosomes, and traffics through the secretory pathway to the plasma membrane and to the endocytic pathway from the plasma membrane. ATG9A protects cells against plasma membrane damage caused by a spectrum of exogenous and endogenous agents, including permeabilization by gasdermin and mixed lineage kinase domain like (MLKL), which generate pores at the plasma membrane or perturb plasma membrane integrity, respectively, during programmed cell death processes of pyroptosis and necroptosis. We furthermore define the ATG9A-IQGAP1 apparatus that integrates with the ESCRT system to cooperatively heal areas of plasma membrane damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 94 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: Q7Z3C6