Recombinant ATG4B antibody

Catalog No. ABIN7828033

This Rabbit Monoclonal antibody specifically detects ATG4B in WB, IHC and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant ATG4B antibody (ABIN7828033)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ATG4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: A447

Product Details anti-ATG4B Antibody

Purpose: Recombinant ATG4B Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human ATG4B fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:200-1:1000,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Alternative Name: ATG4B

Background: AUTL,KIAA,ATG4B,APG4B,AUTL1,cysteine protease ATG4B,KIAA0943,APG4B,AUTL1,cysteine protease ATG4B,APG4 autophagy 4 homolog B,ATG4 autophagy related 4 homolog B (S. cerevisiae),AUT like 1 cysteine endopeptidase,AUT-like 1 cysteine endopeptidase,Autophagin 1,Autophagin-1,Autophagy related 4B cysteine peptidase,Autophagy related cysteine endopeptidase 1,Autophagy related protein 4 homolog B,Autophagy-related cysteine endopeptidase 1,Autophagy-related protein 4 homolog B,hAPG4B,MGC1353,ATG4B is a member of the autophagin protein family. Its cysteine protease activity is required for the cytoplasm to vacuole transport (Cvt) and autophagy. ATG4B cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 44 kDa

Observed MW: 44 kDa

UniProt: Q9Y4P1

Pathways: Autophagy