Recombinant ATG4B antibody

Catalog No. ABIN7828034

The Rabbit Monoclonal anti-ATG4B antibody is suitable to detect ATG4B in samples from Human and Mouse. It has been validated for WB and IF.

Quick Overview for Recombinant ATG4B antibody (ABIN7828034)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ATG4B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: A343

Product Details anti-ATG4B Antibody

Purpose: Recombinant ATG4B Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human ATG4B fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Alternative Name: ATG4B

Background: AUTL,KIAA,ATG4B,APG4B,AUTL1,cysteine protease ATG4B,KIAA0943,APG4B,AUTL1,cysteine protease ATG4B,APG4 autophagy 4 homolog B,ATG4 autophagy related 4 homolog B (S. cerevisiae),AUT like 1 cysteine endopeptidase,AUT-like 1 cysteine endopeptidase,Autophagin 1,Autophagin-1,Autophagy related 4B cysteine peptidase,Autophagy related cysteine endopeptidase 1,Autophagy related protein 4 homolog B,Autophagy-related cysteine endopeptidase 1,Autophagy-related protein 4 homolog B,hAPG4B,MGC1353,Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 48 kDa

Observed MW: 48 kDa

UniProt: Q9Y4P1

Pathways: Autophagy