Recombinant Caspase 7 antibody

Catalog No. ABIN7828070

The Rabbit Monoclonal anti-Caspase 7 antibody is suitable to detect Caspase 7 in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for Recombinant Caspase 7 antibody (ABIN7828070)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Caspase 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A151

Product Details anti-Caspase 7 Antibody

Purpose: Recombinant Caspase-7 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Caspase-7 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: Caspase-7

Background: MCH,LICE,Caspase-7 subunit p,ICE-like apoptotic protease,ICE-LAP,ICE LAP,CMH,CASP7,CASP-7,CMH-1,ICE-LAP3,LICE2,MCH3,caspase-7,Apoptotic protease MCH3,Apoptotic protease Mch-3,Caspase 7,Caspase 7 apoptosis related cysteine peptidase,Caspase7,Caspase-7 subunit p11,CMH 1,CMH1,ICE LAP3,ICE-like apoptotic protease 3,Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 34 kDa

Observed MW: 18, 32, 35 kDa The actual band is not consistent with the expectation.

UniProt: P55210

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity