Recombinant CD7 antibody

Catalog No. ABIN7828091

The Rabbit Monoclonal anti-CD7 antibody is suitable to detect CD7 in samples from Human. It has been validated for FACS, WB, IF and IHC.

Quick Overview for Recombinant CD7 antibody (ABIN7828091)

Target: CD7

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD7 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Clone: A468

Product Details anti-CD7 Antibody

Purpose: Recombinant CD7 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CD7 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD7

Target: CD7

Alternative Name: CD7

Background: T cell antigen CD,T cell surface antigen Leu,LEU,CD7,GP40,LEU-9,TP41,Tp40,CD7 antigen,CD7 antigen (p41),CD7 Molecule,CD7_HUMAN,LEU 9,LEU9,p41 protein,T cell antigen CD7,T cell leukemia antigen,T cell surface antigen Leu 9,T-cell antigen CD7,T-cell leukemia antigen,T-cell surface antigen Leu-9,Tp 40,CD7,CD7 antigen (p41),CD7 antigen,CD7 Molecule,CD7_HUMAN,GP40,LEU 9,LEU9,p41 protein,T cell antigen CD7,T cell leukemia antigen,T cell surface antigen Leu 9,T-cell antigen CD7,T-cell leukemia antigen,T-cell surface antigen Leu-9,Tp 40,Tp40,TP41,The CD7 antigen is a membrane-embedded glycoprotein with a molecular weight of 37-40 kDa and a member of the immunoglobulin supergene family. It plays an important role in T-cell and T-cell/B-cell interactions during early lymphoid development. CD7 is the earliest T-cell-associated molecule to appear in stem cells and prethymic stages and extends its expression all the way to the mature T cells. This molecule is also present on NK cells. In addition, the pluripotent bone marrow stem cells may express CD7. A subpopulation of AML, particularly those with monocytic or megakaryocytic differentiation, may express CD7. Lack of CD7 expression can be used for the detection of T-cell lymphoproliferative disorders, such as mycosis fungoides/Sezary syndrome and adult T-cell leukemia/lymphoma. However, normal and reactive T cells often demonstrate variable degree of CD7 loss. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 25 kDa

Observed MW: 37-40 kDa The actual band is not consistent with the expectation.

UniProt: P09564

Pathways: Cell-Cell Junction Organization