Recombinant CX3CR1 antibody

Catalog No. ABIN7828107

The Rabbit Monoclonal anti-CX3CR1 antibody (Clone A576) (ABIN7828107) specifically detects CX3CR1 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant CX3CR1 antibody (ABIN7828107)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A576

Product Details anti-CX3CR1 Antibody

Purpose: Recombinant CX3CR1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CX3CR1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1

Background: GPR,CCRL,GPRV,CX3CR,CMKDR,CMKBRL,CX3CR1,CCRL1,CMKBRL1,CMKDR1,GPR13,GPRV28,V28,Beta chemokine receptor-like 1,CMK-BRL1,CMK-BRL-1,CX3C chemokine receptor 1,C-X3-C CKR-1,C-X3-C motif chemokine receptor 1,fractalkine receptor,G-protein coupled receptor 13,CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 40 kDa

Observed MW: 50 kDa The actual band is not consistent with the expectation.

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin