Recombinant CBX2 antibody
Quick Overview for Recombinant CBX2 antibody (ABIN7828110)
Target
See all CBX2 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Recombinant CBX2 Monoclonal Antibody
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Purification
- Protein A purified
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Immunogen
- Synthetic peptide derived from the human CBX2 protein
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Isotype
- IgG, kappa
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Application Notes
- WB 1:500-1:1000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Expiry Date
- 12 months
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- CBX2 (Chromobox Homolog 2 (CBX2))
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Alternative Name
- CBX2
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Background
- CBX,CDCA,SRXY,CBX2,CDCA6,M33,SRXY5,Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Molecular Weight
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Calculated MW: 25 kDa
Observed MW: 25 kDa
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UniProt
- Q14781
Target
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