Recombinant C4B antibody

Catalog No. ABIN7828130

The Rabbit Monoclonal anti-C4B antibody is suitable to detect C4B in samples from Human. It has been validated for WB and IHC.

Quick Overview for Recombinant C4B antibody (ABIN7828130)

Target: C4B (C4b) (Complement Component C4b (C4b))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This C4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A146

Product Details anti-C4B Antibody

Purpose: Recombinant Complement C4-B Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Complement C4-B fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for C4B

Target: C4B (C4b) (Complement Component C4b (C4b))

Alternative Name: Complement C4-B

Background: CPAMD,Basic C,Basic C4,C4(Chido Blood Group),C4-B,C4B,C4B_2,CO4,CPAMD3,Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 193 kDa

Observed MW: 193, 85 kDa The actual band is not consistent with the expectation.

UniProt: P0C0L5

Pathways: Complement System