Recombinant CDK1 antibody

Catalog No. ABIN7828142

The Rabbit Monoclonal anti-CDK1 antibody is suitable to detect CDK1 in samples from Human, Mouse, Rat and Green Monkey. It has been validated for WB, IHC, IF and FACS.

Quick Overview for Recombinant CDK1 antibody (ABIN7828142)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat, Green Monkey

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A685

Product Details anti-CDK1 Antibody

Purpose: Recombinant CDK1/Cdc2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CDK1/Cdc2 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IHC 1:50-1:100,IF 1:50-1:100,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Alternative Name: CDK1/Cdc2

Background: CDC,CDK,CDKN,cyclin-dependent kinase,P34CDC,CDK1,CDC2,CDC28A,P34CDC2,cyclin-dependent kinase 1,CDKN1,CDC2,CDC28A,cyclin-dependent kinase 1,P34CDC2,cyclin dependent kinase 1874,CDC2, also named as CDK1, belongs to the protein kinase superfamily. The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of cdc2 at Thr161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of cdc2 at Thr14 and Tyr15. Phosphorylation at Thr14 and Tyr15, resulting in inhibition of cdc2, can be carried out by Wee1 and Myt1 protein kinases. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 34 kDa

Observed MW: 34 kDa

UniProt: P06493

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA