Recombinant EGR2 antibody

Catalog No. ABIN7828167

The Rabbit Monoclonal anti-EGR2 antibody (Clone A776) (ABIN7828167) specifically detects EGR2 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant EGR2 antibody (ABIN7828167)

Target: EGR2 (Early Growth Response 2 (EGR2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EGR2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A776

Product Details anti-EGR2 Antibody

Purpose: Recombinant EGR2 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for EGR2

Target: EGR2 (Early Growth Response 2 (EGR2))

Alternative Name: EGR2

Background: EGR,KROX,EGR2,AT591,CMT1D,CMT4E,KROX20,DKFZp686J1957,Drosophila,E3 SUMO-protein ligase EGR2,early growth response 2,Early growth response protein 2,EGR-2,FLJ14547,homolog (early growth response-2),KROX 20 Drosophila homolog,Krox 20 homolog Drosophila,KROX-20,Krox20 protein,Zinc finger protein Krox-20,EGR2 is also named as KROX20, belongs to the EGR C2H2-type zinc-finger protein family. As a zinc finger transcription factor, it is observed in both the somata and dendrites of central neurons. EGR2 plays an important role in the transient formation of hindbrain developmental compartments or rhombomeres and is also an important factor in peripheral myelination, maintenance of synaptic plasticity and long-term potentiation. EGR2 expression is induced downstream of TCR signaling in NKT precursors and EGR2 is directly connected with the key molecular checkpoints defining NKT lineage commitment and stage progression, suggesting that EGR2 not only induces the early lineage-defining transcription factor PLZF, but also controls the downstream expression of the IL-2Rβ chain. EGR2 is regulated by both soluble and membrane-bound neuregulins and its concentration is partially modulated by calcium-dependent events. EGR2/Krox20 is also required for induction of Pmp22, and is nuclear-localized. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 50 kDa

Observed MW: 55 kDa The actual band is not consistent with the expectation.

UniProt: P11161