Recombinant FGFR3 antibody

Catalog No. ABIN7828206

The Rabbit Monoclonal anti-FGFR3 antibody (Clone A492) (ABIN7828206) specifically detects FGFR3 in WB and IP. The antibody is reactive with Human samples.

Quick Overview for Recombinant FGFR3 antibody (ABIN7828206)

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FGFR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: A492

Product Details anti-FGFR3 Antibody

Purpose: Recombinant FGFR3 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human FGFR3 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000,IP 1:25-1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for FGFR3

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Alternative Name: FGFR3

Background: CEK,JTK,Fibroblast growth factor receptor,ACH,CD333,CEK2,HSFGFR3EX,JTK4,FGFR3,FGFR-3,Fibroblast growth factor receptor 3,IIIc,ACH,CD333,FGFR3,Fibroblast growth factor receptor 3,HSFGFR3EX,JTK4,CD 333,CD333 antigen,CEK 2,FGFR 3,Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism),Heparin binding growth factor receptor,Hydroxyaryl protein kinase,JTK 4,MFR 3,SAM 3,Tyrosine kinase JTK 4,Tyrosine kinase JTK4,Z FGFR 3,Fibroblast growth factor receptor 3 is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. The FGFR proteins are involved in a wide array of pathways known to play a significant role in cancer. Activation of these receptors can lead to activation of the RAS-MAPK pathway and the PI3K-AKT pathway, among others. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 88 kDa

Observed MW: 125 kDa The actual band is not consistent with the expectation.

UniProt: P22607

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding