Recombinant Glutamate Receptor 3 antibody

Catalog No. ABIN7828228

This Rabbit Monoclonal antibody specifically detects Glutamate Receptor 3 in WB. It exhibits reactivity toward Rat and Mouse.

Quick Overview for Recombinant Glutamate Receptor 3 antibody (ABIN7828228)

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Antibody Type: Recombinant Antibody

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A661

Product Details anti-Glutamate Receptor 3 Antibody

Purpose: Recombinant Glutamate receptor 3 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Glutamate receptor 3 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Alternative Name: Glutamate receptor 3

Background: MRX,GRIA,GLUR,GluA,GLUR-K,GRIA3,GLUR-C,GLUR-K3,GLUR3,GLURC,GluA3,MRX94,AMPA 3,AMPA selective glutamate receptor 3,AMPA-selective glutamate receptor 3,dJ1171F9.1,GLUK3,GluR 3,GLUR C,GLUR K3,GluR-3,Glutamate ionotropic receptor AMPA type subunit 3,Glutamate receptor,Glutamate receptor 3,Glutamate receptor C,Glutamate receptor ionotrophic AMPA 3,Glutamate receptor ionotropic,Glutamate receptor subunit 3,GRIA 3,Ionotrophic Glutamate Receptor,ionotropic,AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Glutamate receptor 3 (GluR3) knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Rett's syndrome, amyotrophic lateral sclerosis and Alzheimer disease. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 101 kDa

Observed MW: 101 kDa

UniProt: P42263

Pathways: PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane