Recombinant IL-4 antibody

Catalog No. ABIN7828326

The Rabbit Monoclonal anti-IL-4 antibody (Clone A554) (ABIN7828326) specifically detects IL-4 in WB, FACS and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant IL-4 antibody (ABIN7828326)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: A554

Product Details anti-IL-4 Antibody

Purpose: Recombinant IL-4 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human IL-4 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4

Background: Interleukin,B-cell growth factor,BSF,IL4,BCGF-1,BCGF1,BSF-1,BSF1,IL-4,B-cell growth factor 1,B-cell IgG differentiation factor,B-cell stimulatory factor 1,Binetrakin,IGG1 induction factor,Interleukin-4,Lymphocyte stimulatory factor 1,Pitrakinra,IL2,IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 17 kDa

Observed MW: 14 kDa The actual band is not consistent with the expectation.

UniProt: P05112

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation