Recombinant KIF5B antibody

Catalog No. ABIN7828346

The Rabbit Monoclonal anti-KIF5B antibody is suitable to detect KIF5B in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for Recombinant KIF5B antibody (ABIN7828346)

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KIF5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A605

Product Details anti-KIF5B Antibody

Purpose: Recombinant KIF5B Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human KIF5B fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for KIF5B

Target: KIF5B (Kinesin Family Member 5B (KIF5B))

Alternative Name: KIF5B

Background: HEL-S,KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC,KIF5B is a member of kinesin superfamily protein 5 (KIF5). KIF5 consists of three family members referred to as KIF5A, KIF5B, and KIF5C. KIF5A and KIF5C are specifically expressed in neurons whereas KIF5B is expressed ubiquitously. Targeted disruption of the kif5B gene resulted in embryonic lethality. These and other studies demonstrate that KIF5B plays an important role in the localization and distribution of major organelles, including the mitochondria and lysosome, and can contribute to autophagy. In addition, gene rearrangements involving KIF5B fusions to ALK and RET have been identified as drivers for lung cancer and other malignancies. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 110 kDa

Observed MW: 110 kDa

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization