Recombinant KDM1B antibody

Catalog No. ABIN7828362

The Rabbit Monoclonal anti-KDM1B antibody (Clone A440) (ABIN7828362) specifically detects KDM1B in WB, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for Recombinant KDM1B antibody (ABIN7828362)

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KDM1B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: A440

Product Details anti-KDM1B Antibody

Purpose: Recombinant LSD2/AOF1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human LSD2/AOF1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for KDM1B

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Alternative Name: LSD2/AOF1

Background: AOF,LSD,C6orf,AOF1,C6orf193,LSD2,KDM1B,LSD2, also known as AOF1, is a Lysine (K)-specific demethylase that is encoded by the KDM1B gene in human. LSD2 demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD2 demethylates both mono- and Dimethylated 'Lys-4' of histone H3. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 92 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: Q8NB78

Pathways: Warburg Effect