KDM1B antibody (N-Term)

Catalog No. ABIN6972250

The Rabbit Polyclonal anti-KDM1B antibody (ABIN6972250) specifically detects KDM1B in WB. The antibody is reactive with Mouse samples.

Quick Overview for KDM1B antibody (N-Term) (ABIN6972250)

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM1B Antibody

Binding Specificity: N-Term

Characteristics: KDM1B / LSD2 (Lysine (K)-Specific Demethylase 1B / Lysine-Specific Histone Demethylase 2) is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (By similarity). KDM1B / LSD2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of mouse KDM1B / LSD2.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for KDM1B

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Alternative Name: KDM1B / LSD2

Molecular Weight: 93 kDa

NCBI Accession: NP_758466

Pathways: Warburg Effect