Recombinant KARS antibody

Catalog No. ABIN7828367

The Rabbit Monoclonal anti-KARS antibody is suitable to detect KARS in samples from Human, Mouse and Rat. It has been validated for WB, IHC, IF and IP.

Quick Overview for Recombinant KARS antibody (ABIN7828367)

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A291

Product Details anti-KARS Antibody

Purpose: Recombinant LysRS Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human LysRS fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,IP 1:25-1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Alternative Name: LysRS

Background: DFNB,KIAA,KARS,CMTRIB,DFNB89,KARS1,KARS2,KRS,EC 6.1.1.6,KARS 1,KARS 2,Lysine tRNA ligase,Lysine--tRNA ligase,LysRS,Lysyl-tRNA synthetase,SYK,KIAA0070,Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3(Lys), the primer for reverse transcription initiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 75 kDa

Observed MW: 75 kDa

UniProt: Q15046