Recombinant MBD2 antibody

Catalog No. ABIN7828386

The Rabbit Monoclonal anti-MBD2 antibody (Clone A621) (ABIN7828386) specifically detects MBD2 in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant MBD2 antibody (ABIN7828386)

Target: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MBD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A621

Product Details anti-MBD2 Antibody

Purpose: Recombinant MBD2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MBD2 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IHC 1:200-1:1000,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MBD2

Target: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Alternative Name: MBD2

Background: MBD,NY-CO,MBD2,DMTase,NY-CO-41,DKFZp586O0821,MBD2, also named as DMTase, binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. MBD2 binds hemi-methylated DNA as well. It recruits histone deacetylases and DNA methyltransferases. MBD2 acts as transcriptional repressor and plays a role in gene silencing. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 43 kDa

Observed MW: 43, 29 kDa The actual band is not consistent with the expectation.

UniProt: Q9UBB5

Pathways: Chromatin Binding