Recombinant MTAP antibody

Catalog No. ABIN7828387

This Rabbit Monoclonal antibody specifically detects MTAP in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant MTAP antibody (ABIN7828387)

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MTAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A519

Product Details anti-MTAP Antibody

Purpose: Recombinant MTAP Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MTAP fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:3000,IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Alternative Name: MTAP

Background: HEL,MTAP,BDMF,DMSFH,DMSMFH,HEL-249,LGMBF,MSAP,c86fus,5' methylthioadenosine phosphorylase,5''-methylthioadenosine phosphorylase,Epididymis luminal protein 249,HEL 249,MeSAdo phosphorylase,Methylthioadenosine phosphorylase,MTA phosphorylase,MTAPase,S methyl 5 thioadenosine phosphorylase,S methyl 5' thioadenosine phosphorylase,S-methyl-5''-thioadenosine phosphorylase,MTAP is an enzyme essential for the salvage pathway for both adenine and methionine synthesis. MTAP catalyzes the cleavage of 5'-methylthioadenosine into adenine and 5-methylthio-D-ribose-1-phosphate. Adenine is then used to generate AMP whereas 5-methylthio-D-ribose-1-phosphate is converted into methionine. MTAP is expressed in all normal cells and tissues, although frequently lost in different human tumors including pancreatic adenocarcinoma, neuroendocrine tumors, non-small cell lung carcinoma and breast carcinoma, thereby implicating its potential function as a tumor suppressor. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 31 kDa

Observed MW: 31 kDa

UniProt: Q13126

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process