Recombinant MCM3 antibody

Catalog No. ABIN7828390

This Rabbit Monoclonal antibody specifically detects MCM3 in WB, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant MCM3 antibody (ABIN7828390)

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MCM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: A296

Product Details anti-MCM3 Antibody

Purpose: Recombinant MCM3 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MCM3 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000,IP 1:25-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MCM3

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Alternative Name: MCM3

Background: HCC,DNA replication licensing factor MCM,DNA polymerase alpha holoenzyme-associated protein P,P1-MCM,MCM,MCM3,HCC5,P1-MCM3,P1.h,RLFB,MCM 3,P1 Protein,P102 protein,p102,DNA replication licensing factor MCM3,DNA polymerase alpha holoenzyme-associated protein P1,RLF subunit beta,Cervical cancer proto oncogene 5,DNA polymerase alpha holoenzyme associated P1,DNA polymerase alpha holoenzyme associated protein P1,DNA replication factor MCM3,HCC 5,hRlf beta subunit,Human cervical cancer proto oncogene 5,MCM3 minichromosome maintenance deficient 3,MGC1157,Minichromosome maintenance complex component 3,Minichromosome maintenance deficient 3,Minichromosome maintenance protein 3,P1 h,P1 MCM3,Replication licensing factor beta subunit,RLF beta subunit,Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 91 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: P25205

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA