Recombinant MCM5 antibody

Catalog No. ABIN7828391

The Rabbit Monoclonal anti-MCM5 antibody is suitable to detect MCM5 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for Recombinant MCM5 antibody (ABIN7828391)

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MCM5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A301

Product Details anti-MCM5 Antibody

Purpose: Recombinant MCM5 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MCM5 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Alternative Name: MCM5

Background: MGC,Cell division cycle,DNA replication licensing factor MCM,Minichromosome maintenance complex component,P1-CDC,P1 CDC,CDC,MCM,MCM5,CDC46,P1-CDC46,CDC 46,CDC46 homolog,Cell division cycle 46,DNA replication licensing factor,DNA replication licensing factor MCM5,MCM 5,MGC5315,Minichromosome maintenance complex component 5,P1 CDC46,DNA replication licensing factor MCM 5,Minichromosome maintenance complex component 5,Minichromosome maintenance deficient (S. cerevisiae) 5,Minichromosome maintenance deficient 5,Minichromosome maintenance deficient protein 5,Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 82 kDa

Observed MW: 82 kDa

UniProt: P33992

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA