Recombinant NFKBIB antibody

Catalog No. ABIN7828421

The Rabbit Monoclonal anti-NFKBIB antibody is suitable to detect NFKBIB in samples from Human and Mouse. It has been validated for WB, IF and FACS.

Quick Overview for Recombinant NFKBIB antibody (ABIN7828421)

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NFKBIB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A563

Product Details anti-NFKBIB Antibody

Purpose: Recombinant IKB beta Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human IKB beta fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,FCM 1:50-1:100,IF 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for NFKBIB

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Alternative Name: IKB beta

Background: TRIP,NFKBIB,IKBB,TRIP9,I kappa B beta,IkappaBbeta,I-kappa-B-beta,IKB beta,IkB-B,IkBbeta,IkB-beta,NF kappa BIB,NF-kappa-B inhibitor beta,NF-kappa-BIB,Thyroid receptor interacting protein 9,Thyroid receptor-interacting protein 9,TR interacting protein 9,TR-interacting protein 9,TRIP-9,IkB-beta a protein of the NF-kappa-B inhibitor family. IKB beta Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with IKB beta-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 60 kDa

Observed MW: 48 kDa The actual band is not consistent with the expectation.

UniProt: Q15653

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades