Recombinant PKC zeta antibody

Catalog No. ABIN7828495

This Rabbit Monoclonal antibody specifically detects PKC zeta in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant PKC zeta antibody (ABIN7828495)

Target: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PKC zeta antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A658

Product Details anti-PKC zeta Antibody

Purpose: Recombinant PKC zeta Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PKC zeta fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PKC zeta

Target: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Alternative Name: PKC zeta

Background: PKC,PRKCZ,PKC-ZETA,PKC2,14-3-3-zetaisoform,AI098070,aPKCzeta,C80388,EC 2.7.11.13,included,KPCZ,nPKC zeta,nPKC-zeta,OTTHUMP00000001368,OTTHUMP00000044160,PKC 2,PKC ZETA,Pkcz,PKC-Z,PKCZETA,PKM-zeta,Protein kinase C zeta,Protein kinase C zeta form,Protein kinase C zeta type,Protein Kinase M Zeta,r14-3-3,R74924,zetaPKC,Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 68 kDa

Observed MW: 70 kDa The actual band is not consistent with the expectation.

UniProt: Q05513

Pathways: NF-kappaB Signaling, RTK Signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling