Recombinant QKI antibody

Catalog No. ABIN7828501

This Rabbit Monoclonal antibody specifically detects QKI in WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant QKI antibody (ABIN7828501)

Target: QKI (Protein Quaking (QKI))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This QKI antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: A575

Product Details anti-QKI Antibody

Purpose: Recombinant QKI Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human QKI fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:3000,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for QKI

Target: QKI (Protein Quaking (QKI))

Alternative Name: QKI

Background: QKI,Hqk,QK,QK1,QK3,hqkI,HKQ,QKI is a member of the signal transduction and activator of RNA (STAR) protein family of RNA-binding proteins. Mutations in the mouse Qki locus results in impaired myelin formation resulting in tremors. QKI proteins exist as homodimers, and disruption of the dimerization process is lethal in mice. QKI exists in different isoforms that differ in their C-terminus, resulting in unique subcellular localizations. The nuclear isoform of QKI, QKI-5, is involved in regulation of alternative splicing of MAG mRNA, which encodes for a protein important for myelin sheath formation and maintenance. QKI has also been implicated in schizophrenia and oligodendrocyte differentiation. QKI can function as a tumor suppressor, as it is regulated by p53 to stabilize miRNAs that regulate TGF-β signaling. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 38 kDa

Observed MW: 38 kDa

UniProt: Q96PU8