Recombinant PTPN12 antibody

Catalog No. ABIN7828502

The Rabbit Monoclonal anti-PTPN12 antibody is suitable to detect PTPN12 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Recombinant PTPN12 antibody (ABIN7828502)

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PTPN12 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A502

Product Details anti-PTPN12 Antibody

Purpose: Recombinant PTPN12 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PTPN12 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PTPN12

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Alternative Name: PTPN12

Background: PTPG,PTPN,PTPG1,PTP-PEST,PTPN12,PTP-PEST,Protein tyrosine phosphatase G1,Protein tyrosine phosphatase non receptor type 12,Protein-tyrosine phosphatase G1,PTN12,PTP PEST,Tyrosine protein phosphatase non receptor type 12,Tyrosine-protein phosphatase non-receptor type 12,PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 88 kDa

Observed MW: 120 kDa The actual band is not consistent with the expectation.

UniProt: Q05209