Recombinant RAP1A + RAP1B antibody

Catalog No. ABIN7828517

The Rabbit Monoclonal anti-RAP1A + RAP1B antibody is suitable to detect RAP1A + RAP1B in samples from Human, Mouse and Rat. It has been validated for WB, IP and IF.

Quick Overview for Recombinant RAP1A + RAP1B antibody (ABIN7828517)

Target: RAP1A + RAP1B

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: A459

Product Details

Purpose: Recombinant RAP1A+RAP1B Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human RAP1A+RAP1B fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000,IF 1:50,IP 1:25-1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details

Target: RAP1A + RAP1B

Alternative Name: RAP1A+RAP1B

Background: RAP,SMGP,Ras-related protein Krev,RAP1A,C21KG,G-22K,KREV-1,KREV1,RAP1,SMGP21,GTP-binding protein smg p21A,member of RAS oncogene family,Ras-related protein 1A,Ras-related protein Krev-1,Ras-related protein Rap-1A,Rap1 is a member of the Ras family of small GTPases. It undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of Rap1 is therefore affected by the balance of intracellular levels of GEFs and GAPs. This protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 21 kDa

Observed MW: 21 kDa

UniProt: P62834