Recombinant Ret Proto-Oncogene antibody

Catalog No. ABIN7828523

The Rabbit Monoclonal anti-Ret Proto-Oncogene antibody is suitable to detect Ret Proto-Oncogene in samples from Human and Mouse. It has been validated for WB.

Quick Overview for Recombinant Ret Proto-Oncogene antibody (ABIN7828523)

Target: Ret Proto-Oncogene (RET)

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Ret Proto-Oncogene antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A548

Product Details anti-Ret Proto-Oncogene Antibody

Purpose: Recombinant Ret Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Ret fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Alternative Name: Ret

Background: MTC,CDHF,CDHR,HSCR,Cadherin family member,RET-ELE,RET,CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1,RET51,Cadherin family member 12,Proto-oncogene c-Ret,Proto-oncogene tyrosine-protein kinase receptor Ret,Proto-oncogene tyrosine-protein kinase receptor Ret,Cadherin family member 12,Proto-oncogene c-Ret,The Ret is a receptor tyrosine kinase that functions as a multicomponent receptor complex in conjunction with other membrane-bound, ligand-binding GDNF family receptors. Ligands that bind the Ret receptor include the glial cell line-derived neurotrophic factor (GDNF) and its congeners neurturin, persephin, and artemin. Research studies have shown that alterations in the corresponding RET gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung's disease. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 124 kDa

Observed MW: 175 kDa The actual band is not consistent with the expectation.

UniProt: P07949

Pathways: RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation