Recombinant Retinoid X Receptor alpha antibody

Catalog No. ABIN7828527

The Rabbit Monoclonal anti-Retinoid X Receptor alpha antibody (Clone A659) (ABIN7828527) specifically detects Retinoid X Receptor alpha in WB and IF. The antibody is reactive with Human samples.

Quick Overview for Recombinant Retinoid X Receptor alpha antibody (ABIN7828527)

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: A659

Product Details anti-Retinoid X Receptor alpha Antibody

Purpose: Recombinant RXRA Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human RXRA fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Alternative Name: RXRA

Background: NR2B,NR2B1,RXRA,Retinoid X receptor alpha,Retinoid X receptor α (RXRA) is the founding RXR family member and is predominantly expressed in the liver, kidney, epidermis, intestine, and a variety of tissues. Knockout of the murine rxrα gene results in embryonic lethality tentatively due to myocardial hypoplasia, which demonstrates the importance of RXRA in retinoid signalingin vivo. Biochemical evidence suggests that RXRA transcriptional activity is post-translationally regulated through the Ras-Raf-MAPK signaling cascade. MAPK-dependent phosphorylation of RXRα directly abrogates the ability of RXRA to associate with nuclear receptor coactivators. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 51 kDa

Observed MW: 56 kDa The actual band is not consistent with the expectation.

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C