Recombinant RNF2 antibody

Catalog No. ABIN7828532

The Rabbit Monoclonal anti-RNF2 antibody is suitable to detect RNF2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, IF and FACS.

Quick Overview for Recombinant RNF2 antibody (ABIN7828532)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RNF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A531

Product Details anti-RNF2 Antibody

Purpose: Recombinant RING1B Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human RING1B fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:200-1:1000,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: RING1B

Background: RNF,DinG,Ring1b,Rnf2,RING1B is a E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. It may be involved in the initiation of both imprinted and random X inactivation. It E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 38 kDa

Observed MW: 38 kDa

UniProt: Q9CQJ4