Recombinant S100A8 antibody

Catalog No. ABIN7828542

The Rabbit Monoclonal anti-S100A8 antibody (Clone A427) (ABIN7828542) specifically detects S100A8 in WB, IHC and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant S100A8 antibody (ABIN7828542)

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This S100A8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: A427

Product Details anti-S100A8 Antibody

Purpose: Recombinant S100A8 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human S100A8 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:200-1:1000,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for S100A8

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Alternative Name: S100A8

Background: Protein S100-A,S100a,Kcnip,KCHIP,MRP,S100A8,60B8AG,CAGA,CFAG,CGLA,CP-10,L1Ag,MA387,MIF,MRP8,NIF,P8,Calgranulin A,Calgranulin-A,Cystic fibrosis antigen,Leukocyte L1 complex light chain,MRP-8,Protein S100-A8,CALP,KCNIP4,KCHIP4,AI323541,B8Ag,BEE11,Calprotectin,Calprotectin L1L subunit,Chemotactic cytokine CP-10,included,Migration inhibitory factor-related protein 8,Myeloid-related protein 8,Neutrophil cytosolic 7 kDa protein,Pro-inflammatory S100 cytokine,S100 calcium binding protein A8,S100 calcium binding protein A8 (calgranulin A),S100 calcium-binding protein A8,S100A8/S100A9 complex,S10A8,Urinary stone protein band A,MRP8/S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. MRP8 has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic. The extracellular functions involve proinflammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its proinflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 11 kDa

Observed MW: 11 kDa

UniProt: P05109

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins