Recombinant SIRT2 antibody

Catalog No. ABIN7828567

This Rabbit Monoclonal antibody specifically detects SIRT2 in WB and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Recombinant SIRT2 antibody (ABIN7828567)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SIRT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A435

Product Details anti-SIRT2 Antibody

Purpose: Recombinant SIRT2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human SIRT2 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Alternative Name: SIRT2

Background: SIR,SIRT,sirtuin,SIRT2,SIR2,SIR2L,SIR2L2,sirtuin 2,NAD-dependent protein deacetylase sirtuin-2,Regulatory protein SIR2 homolog 2,SIR2-like protein 2,Sirtuin type 2,NAD-dependent protein deacetylase sirtuin-2 (SIRT2) is a NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. SIRT2 participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. SIRT2 plays a major role in the control of cell cycle progression and genomic stability. It also functions in the antephase checkpoint preventing precocious mitotic entry in response to microtubule stress agents, and hence allowing proper inheritance of chromosomes. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 43 kDa

Observed MW: 36, 43 kDa The actual band is not consistent with the expectation.

UniProt: Q8IXJ6