Recombinant UBE2K antibody

Catalog No. ABIN7828658

The Rabbit Monoclonal anti-UBE2K antibody is suitable to detect UBE2K in samples from Human. It has been validated for WB.

Quick Overview for Recombinant UBE2K antibody (ABIN7828658)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UBE2K antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A412

Product Details anti-UBE2K Antibody

Purpose: Recombinant HIP2/LIG Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human HIP2/LIG fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Alternative Name: HIP2/LIG

Background: HIP,UBC,UBE2K,E2-25K,HIP2,HYPG,LIG,UBC1,HIP-2,Huntingtin-Interacting Protein 2,Ubiquitin Carrier Protein,Ubiquitin-Conjugating Enzyme E2 K,Ubiquitin-Conjugating Enzyme E2(25K),Ubiquitin-Conjugating Enzyme E2-25 kDa,Ubiquitin-Conjugating Enzyme E2-25K,Ubiquitin-Protein Ligase,Huntingtin-interacting protein 2 (HIP2/LIG), is a E2 ubiquitin-conjugating enzyme, which accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, HIP2/LIG catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, while it does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Moreover, HIP2/LIG mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 22 kDa

Observed MW: 22 kDa

UniProt: P61086