Recombinant VWF antibody

Catalog No. ABIN7828674

The Rabbit Monoclonal anti-VWF antibody (Clone A683) (ABIN7828674) specifically detects VWF in IHC and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant VWF antibody (ABIN7828674)

Target: VWF (Von Willebrand Factor (VWF))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This VWF antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: A683

Product Details anti-VWF Antibody

Purpose: Recombinant Von Willebrand Factor Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Von Willebrand Factor fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:5000-1:10000,IHC 1:100-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: Von Willebrand Factor

Background: F8VWF,VWD,von Willebrand factor,von Willebrand antigen II,Vwf,VWF (Von Willebrand factor) is a multimeric plasma glycoprotein that promotes adhesion of platelets to sites of vascular injury. Mature circulating VWF is made up of disulfide-bonded multimers that are in a complex with factor VIII. VWF is stored in secretory Weibel-Palade bodies in endothelial cells. It is synthesized as a large precursor protein and undergoes extensive posttranslational modifications including dimerization in the endoplasmic reticulum followed by cleavage of the pro-peptide and multimerization in the Golgi apparatus. VWF is important in hemostasis, and genetic defects in the structure and modification of VWF can cause von Willebrand disease (VWD), the most common congenital bleeding disorder in humans. Alternatively, increased levels of VWF have been shown to be involved in acute coronary thrombosis and are a clinical risk marker for atherosclerosis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 309 kDa

Observed MW: 309 kDa

UniProt: Q8CIZ8