Recombinant ZNF259 antibody

Catalog No. ABIN7828682

The Rabbit Monoclonal anti-ZNF259 antibody is suitable to detect ZNF259 in samples from Human. It has been validated for WB.

Quick Overview for Recombinant ZNF259 antibody (ABIN7828682)

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ZNF259 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A747

Product Details anti-ZNF259 Antibody

Purpose: Recombinant ZPR1 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for ZNF259

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Alternative Name: ZPR1

Background: ZPR,MGC,Zinc finger protein,Zinc finger protein ZPR,ZNF,ZPR1,ZNF259,MGC110983,Zinc finger protein 259,Zinc finger protein ZPR1,ZNF 259,The zinc finger protein ZPR1 (ZNF259) binds to epidermal growth factor receptor (EGFR) and is localized to both cytoplasm and nucleus. The zinc fingers found in ZPR1 and the tyrosine kinase domain of EGFR mediate the interaction between ZPR1 and the receptor (1). ZPR1 translocates from the cytoplasm to nucleus following mitogen (i.e. EGF) stimulation (2,3). ZPR1 also interacts with translation elongation factor eEF1A in vivo following EGF treatment (3). The interaction between the zinc finger protein and elongation factor is important for cell proliferation. Cells lacking ZPR1 exhibit abnormal nucleolar function, suggesting that ZPR1 is required for cell viability and nucleolar function in dividing cells (3). ZPR1 knockout mice exhibit significant neurodegeneration, and reduced or altered expression of ZPR1 may contribute to spinal muscular atrophy, a disorder characterized by degeneration of spinal cord neurons (4). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 51 kDa

Observed MW: 53 kDa The actual band is not consistent with the expectation.

UniProt: O75312