CD40 antibody

Catalog No. ABIN7828765

This Rabbit Monoclonal antibody specifically detects CD40 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD40 antibody (ABIN7828765)

Target: CD40

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD40 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 5D12

Product Details anti-CD40 Antibody

Purpose: Purified Anti-Human CD40 Antibody[5D12]

Purification: >98%, Protein A/G purified

Purity: >98 %

Immunogen: Recombinant Human CD40 protein

Isotype: IgG

Application Details

Application Notes: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: CDW,B-cell surface antigen CD,Tumor necrosis factor receptor superfamily member,TNFRSF,CD40,Bp50,CDW40,TNFRSF5,p50,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor,TNFRSF5,AI326936,B cell associated molecule CD40,B cell surface antigen CD40,B cell-associated molecule,CD 40,CD40 (protein),CD40 antigen,CD40 antigen (TNF receptor superfamily member 5),CD40 Molecule,CD40 protein,CD40 type II isoform,GP39,HIGM1,IGM,IMD3,isoform CRA_a,member 5,MGC9013,Nerve growth factor receptor related B lymphocyte activation molecule,OTTHUMP00000031699,OTTHUMP00000031700,TBAM,T-BAM,TNF receptor superfamily member 5,TNR5,TRAP,Tumor necrosis factor receptor superfamily,Tumor necrosis factor receptor superfamily member 5 precursor,CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature hCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 62 aa cytoplasmic domain . Human and mouse CD40 share 62 % aa identity. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints