Integrin beta 3 antibody (APC)

Catalog No. ABIN7828794

The APC-conjugated Mouse Monoclonal anti-Integrin beta 3 antibody (Clone HIP11) (ABIN7828794) specifically detects Integrin beta 3 in FACS. The antibody is reactive with Human samples.

Quick Overview for Integrin beta 3 antibody (APC) (ABIN7828794)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: HIP11

Product Details anti-Integrin beta 3 Antibody (APC)

Purpose: APC Anti-Human CD61 Antibody[HIP11]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Control: E-AB-F09792E

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Handling Advice: Please protected from prolonged exposure to light and do not freeze

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: CD61

Background: Integrin β3, gpIIIa,AN00657,CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins. Cat.No. Product Name Sizes E-CK-A105 10xACK Lysis Buffer 500 mL , 200 mL , 100 mL E-CK-A107 Cell Staining Buffer 500 mL , 200 mL , 100 mL Cat.No. Product Name Clone No. E-AB-F1166E APC Anti-Human CD61 Antibody[VI-PL2] VI-PL2 IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Gene ID: 3690

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex