IL3RA antibody (PE)

Catalog No. ABIN7828820

The Rat Monoclonal anti-IL3RA antibody is suitable to detect IL3RA in samples from Mouse. It has been validated for FACS.

Quick Overview for IL3RA antibody (PE) (ABIN7828820)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL3RA antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 5B11

Product Details anti-IL3RA Antibody (PE)

Purpose: PE Anti-Mouse CD123 Antibody[5B11]

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Control: E-AB-F09832D

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Handling Advice: Please protected from prolonged exposure to light and do not freeze

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: CD123

Background: IL-3 Receptor α chain,IL-3Rα,CD123 is a 70 kD α chain subunit of the IL-3 receptor (IL-3R α). It is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL-3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either the common β chain (CDw131) or the IL-3R β chain (AIC2A) to form high-affinity heterodimeric IL-3 receptors. CDw131 can complex with the α subunits of the mouse IL-3R, IL-5R and GM-CSFR to form high-affinity receptors, while the IL-3 R β subunit is specific for IL-3 but binds with low affinity. IL-3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. The 5B11 antibody does not block binding of IL-3 to the high affinity IL-3 receptor. Cat.No. Product Name Sizes E-CK-A105 10xACK Lysis Buffer 500 mL , 200 mL , 100 mL E-CK-A107 Cell Staining Buffer 500 mL , 200 mL , 100 mL Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Gene ID: 16188

UniProt: Q8CII2

Pathways: JAK-STAT Signaling