SIRPA antibody (PE-Cy5)

Catalog No. ABIN7828837

This Mouse Monoclonal antibody specifically detects SIRPA in FACS. It exhibits reactivity toward Rat.

Quick Overview for SIRPA antibody (PE-Cy5) (ABIN7828837)

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRPA antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Clone: OX-41

Product Details anti-SIRPA Antibody (PE-Cy5)

Purpose: PE/Cyanine5 Anti-Rat CD172a(SIRPα) Antibody[OX-41]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Control: E-AB-F09792G

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.

Handling Advice: Please protected from prolonged exposure to light and do not freeze

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for SIRPA

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Alternative Name: CD172a

Background: SIRPa, PTPNS1, BIT, MFR, p84, CD172 antigen-like family member A,AN00652,Rat CD172a, also known as a signal-regulatory protein (SIRP), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a. Cat.No. Product Name Sizes E-CK-A105 10xACK Lysis Buffer 500 mL , 200 mL , 100 mL E-CK-A107 Cell Staining Buffer 500 mL , 200 mL , 100 mL Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Gene ID: 19261

UniProt: P97710